The San Diego Padres host the LA Dodgers at Petco Park on Tuesday. Both teams have enjoyed fine starts to the 2026 MLB season, sitting first and second in the NL West, respectively.
The Friars secured a hard-fought win in the series opener, thanks to a stellar performance from Michael King and a first-inning homer from Miguel Andujar.
Let’s look at the odds, preview, prediction and best betting tips for the game.
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MLB: San Diego Padres vs LA Dodgers odds
Money Line: San Diego Padres (+135), LA Dodgers (-163)
Run Line: San Diego Padres +1.5 (-122), LA Dodgers +1.5 (+102)
Total Runs: Over 8 (-114), Under 8 (-105)
Preview – Probable starting pitchers and lineups
San Diego Padres probable starting pitcher: Griffin Canning
Griffin Canning gets the starting nod for the hosts. The veteran comes into the game with a 0-2 record and a 10.64 ERA.
San Diego Padres predicted lineup:
- OF Fernando Tatis Jr.
- DH Miguel Andujar
- 1B Gavin Sheets
- 3B Manny Machado
- SS Xander Bogaerts
- OF Jackson Merrill
- OF Nick Castellanos
- OF Ramon Laureano
- C Rodolfo Duran
LA Dodgers probable starting pitcher: Emmet Sheehan
Emmet Sheehan takes the mound for the visitors. He has fared better than his counterpart this year, coming into the matchup with a 3-1 record and a 4.54 ERA.
LA Dodgers predicted lineup:
- DH Shohei Ohtani
- SS Mookie Betts
- 1B Freddie Freeman
- OF Kyle Tucker
- C Will Smith
- 3B Max Muncy
- OF Andy Pages
- OF Teoscar Hernandez
- 2B Hyeseong Kim
The Padres put up an excellent defensive performance to shut out the Dodgers in Monday’s series opener. However, with the pitching matchup clearly leaning in the visitors’ favor this time around, the reigning World Series champions should have enough quality to level the series with an important win.
Prediction: San Diego Padres 4, LA Dodgers 6
Betting Tips
The Dodgers will come into the game desperate to return to winning ways, and they should manage to do just that, perfectly setting up the series finale.
Money Line: LA Dodgers (-163)
Run Line: LA Dodgers -1.5 (+102)
Total Runs: Over 8 (-114)
Likely players to hit home runs: Miguel Andujar (San Diego Padres), Gavin Sheets (San Diego Padres), Shohei Ohtani (LA Dodgers), Freddie Freeman (LA Dodgers)
Edited by Raghav Mehta